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Transcranial alternating current stimulation and its influences on neurophysiological mechanisms of error processing and error regulation in healthy subjects and patients with attention deficit hyperactivity disorder (ADHD)

Transcranial alternating current stimulation and its influences on neurophysiological mechanisms of error processing and error regulation in healthy subjects and patients with attention deficit hyperactivity disorder (ADHD)

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
DRKS
Registry ID
DRKS00008209
Enrollment
75
Registered
2015-05-26
Start date
2015-06-01
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy Subjects F90.0

Interventions

Group 1: Changes after 1 mA 6 hZ for 15 min tACS over pre-supplementary motor area (pre-SMA): on the behavioural level, reaction time, its variability, omission and commission errors will be analysed
Error related negativity and positivity
Power of theta and alpha
On the source level, the harmonic frequency will be analyse using Dynamic Imaging of Coherent Sources. For subjects groups: 1. Healthy adults (Age 18-30, n=25) 2. Healthy children and adolsecnets (Ag
On the source level, the harmonic frequency will be analyse using Dynamic Imaging of Coherent Sources. For subjects groups: 1. Healthy adults (Age 18-30, n=25) 2. Healthy children and adolsecnets (A
On the source level, the harmonic frequency will be analyse using Dynamic Imaging of Coherent Sources. For subjects groups: 1. Healthy adults (Age 18-30, n=25) 2. Healthy children

Sponsors

Institut für Medizinische Psychologie und Medizinische SoziologieUniversitätsklinikum Schleswig-Holstein
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
10 Years to 30 Years

Inclusion criteria

Inclusion criteria: • consent of subjects and their parents • Age 10 - 30 years • Male • right handed. For patients: ICD-10(F90.0)

Exclusion criteria

Exclusion criteria: • internal , neurological and other psychiatric disorders • IQ < 85 • medication • Conduct disorder • seizures ( epilepsy ) , seizures ( even once) , febrile convulsions , increased excitability of the brain ( a history of : epilepsy typical potentials or other patho - logical EEG changes ) • metal implants in the head area ( inserted into the header area metal ) : for example, In - plantation of artificial cochlea ( cochlear ) • condition after head injury with loss of consciousness • Any pre-existing condition of the heart pacemaker • Lack of Compliance

Design outcomes

Primary

MeasureTime frame
On the behavioural level, reaction time, its variability, omission and commission errors will be analysed; Error related negativity and positivity; Power of theta and alpha; On the source level, the harmonic frequency will be analyse using Dynamic Imaging of Coherent Sources. These parameters are recorded for each stimulation condition.—

Secondary

MeasureTime frame
Adverse events questionnaire (1). Wenn: After each experimental session. (1) C. Poreisz, K. Boros, A. Antal, W. Paulus, Safety aspects of transcranial direct current stimulation concerning healthy subjects and patients, Brain Res Bull, 72 (2007) 208-214—

Countries

Germany

Contacts

Public ContactMichael Siniatchkin

Institut für Medizinische Psychologie und Medizinische SoziologieUniversitätsklinikum Schleswig-Holstein

siniatchkin@med-psych.uni-kiel.de04315988751

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026