Level of brain-derived neurotrophic factor during Ramadhan fasting in Germany

Level of brain-derived neurotrophic factor during Ramadhan fasting in Germany - FBDNF

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00008181

Enrollment

Registered

2015-07-13

Start date

2015-06-09

Completion date

Unknown

Last updated

2025-10-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy participants

Interventions

Group 1: One group will do fasting in Ramadhan (fasting group) for one month Group 2: the other group (control) will not do fasting.

Eligibility

Sex/Gender

Male

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: (1) healthy (especially free of pain and psychiatric disorders), (2) be a male gender, (3) older than 18 years of age, (4) be planning to fast the whole month of Ramadan (5) The subjects will not do Ramadhan fasting for the first experience in their life (6) understand German/English language.

Exclusion criteria

Exclusion criteria: If you are suffering from cancer, cardiac disease, depression, acute or inflammatory diseases, diabetes or fresh injuries we are sorry for not being able to recruit you as volunteer/participants.

Design outcomes

Primary

Measure	Time frame
BDNF will bemeasured from serum samples by method of enzyme-linked immunosorbent assay (ELISA). In the fasting group, it will be measured at four time points. The first end point of the study (T1) will be conducted one week before the start of the Ramadan (June 2015). The second session will be conducted on the mid of Ramadan (T2). The third session will be conducted on the last days (T3). Explorative time point will be done at one week after the Ramadan fasting finished (T4). In the control group, there will only be 2 time points for measuring BDNF. It will be before start of the Ramadhan (T1) and on the last days of Ramadhan (T3).	—

Measure

Time frame

BDNF will bemeasured from serum samples by method of enzyme-linked immunosorbent assay (ELISA). In the fasting group, it will be measured at four time points. The first end point of the study (T1) will be conducted one week before the start of the Ramadan (June 2015). The second session will be conducted on the mid of Ramadan (T2). The third session will be conducted on the last days (T3). Explorative time point will be done at one week after the Ramadan fasting finished (T4). In the control group, there will only be 2 time points for measuring BDNF. It will be before start of the Ramadhan (T1) and on the last days of Ramadhan (T3).

—

Secondary

Measure	Time frame
Body composition, Pain intensity (visual analogue scale), fatigue (visual analogue scale). Health related quality of life will be measured by Short-Form-12. Mood related disoreders will be measured by Beck's depression inventory and Hospital and anxiety depression scale, Sleep related quality will be measured by epworth sleepiness scale. In the fasting group, all end points will be measured at four time points. The first end point of the study (T1) will be conducted one week before the start of the Ramadan (June 2015). The second session will be conducted on the mid of Ramadan (T2). The third session will be conducted on the last days (T3). Explorative time point will be done at one week after the Ramadan fasting finished (T4). In the control group, there will only be 2 time points for measuring endpoints. It will be before start of the Ramadhan (T1) and on the last days of Ramadhan (T3).	—

Measure

Time frame

Body composition, Pain intensity (visual analogue scale), fatigue (visual analogue scale). Health related quality of life will be measured by Short-Form-12. Mood related disoreders will be measured by Beck's depression inventory and Hospital and anxiety depression scale, Sleep related quality will be measured by epworth sleepiness scale. In the fasting group, all end points will be measured at four time points. The first end point of the study (T1) will be conducted one week before the start of the Ramadan (June 2015). The second session will be conducted on the mid of Ramadan (T2). The third session will be conducted on the last days (T3). Explorative time point will be done at one week after the Ramadan fasting finished (T4). In the control group, there will only be 2 time points for measuring endpoints. It will be before start of the Ramadhan (T1) and on the last days of Ramadhan (T3).

—

Countries

Germany

Contacts

Public ContactSamaneh Khoshandam Ghashang

Klinik für Rehabilitationsmedizin, Hannover Medical School

Khoshandam-Ghashang.Samaneh@mh-hannover.de+49511-5324121

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026