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Neural and molecular risk mechanisms of autism, affective disorders and psychoses.

Neural and molecular risk mechanisms of autism, affective disorders and psychoses.

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
DRKS
Registry ID
DRKS00008176
Enrollment
500
Registered
2015-06-29
Start date
2015-02-15
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

F20 F31 F33 F84

Interventions

Group 1: 1. Patients: • Study content: The study contains standardized and half standardized interviews to confirm the existences and further characterization of the psychiatric disorder. Furthermor

Sponsors

Zentralinstitut für seelische Gesundheit
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Additional Inclusion Critera: - all subjects: o Sufficient german language abilities o Ability to understand study protocol and give written informed consent - For healthy controls o No diagnosis of any psychiatric disorder according to ICD-10 and DSM-IV o No family history of any psychiatric disorder according to ICD-10 and DSM-IV - For first grade relatives: o First grade relative with the diagnosis of ASD, SZ, BP or MD according to ICD-10 or DSM-IV - For patients: o Diagnosis of ASD, SZ, BP or MD according to ICD-10 or DSM-IV Exclusion Criteria:

Exclusion criteria

Exclusion criteria: Exclusion Criteria: - For women: pregnancy - MR exclusion criteria (metal implants, brain surgery, permanent makeup) - Current alcohol or drug abuse - For healthy controls and first degree relatives: psychiatric disorder according to ICD-10 or DSM-IV

Design outcomes

Primary

MeasureTime frame
Identification of multivariate neurocognitive markers, that allow the transdiagnostic classification of patient subgroups according to biological criteria

Secondary

MeasureTime frame
Find evidence for genetic contributions to disorder-specific and transdiagnostic neurocognitve markers.

Countries

Germany

Contacts

Public ContactKristina Otto

Zentralinstitut für seelische Gesundheit

kristina.otto@zi-mannheim.de+49-621-1703-6522

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026