Registration of a aqueous humor-cytokine and -protein profile in glaucoma

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00008120

Enrollment

200

Registered

2015-05-18

Start date

2015-05-20

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

H40.1 H40.8

Interventions

Group 1: Glaucoma patients: development of a profile of proteins and growth factors from the aqueous humor Group 2: Healthy controls (other ophthalmologic disease): development of a profile of protei

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. all types of primary and secondary glaucoma and healthy controls. 2. Requirement for cataract-, glaucoma- or corneal surgery.

Exclusion criteria

Exclusion criteria: 1. No need for ophthalmo-surgery. 2. No signed declaration of consent.

Design outcomes

Primary

Measure	Time frame
Aim of the study: Measurement and comparison of intraocular proteins by intraoperative aqueous humor-extraction in patients with primary and secondary open-angle glaucoma and healthy age-matched controls who need ophthalmo-surgery because of other diseases. Study schedule: It is planned to recruit 200 probes from the routine patient base at the Department of Ophthalmology, University of Cologne, Germany. The probe-extraction will only be performed if a standard ophthalmo-surgery is necessary. The protein- and cytokine-profiles will be analysed by mass spectrometry, antibody array analysis, multiplex microbead assay and ELISA.	—

Measure

Time frame

Aim of the study: Measurement and comparison of intraocular proteins by intraoperative aqueous humor-extraction in patients with primary and secondary open-angle glaucoma and healthy age-matched controls who need ophthalmo-surgery because of other diseases. Study schedule: It is planned to recruit 200 probes from the routine patient base at the Department of Ophthalmology, University of Cologne, Germany. The probe-extraction will only be performed if a standard ophthalmo-surgery is necessary. The protein- and cytokine-profiles will be analysed by mass spectrometry, antibody array analysis, multiplex microbead assay and ELISA.

—

Countries

Germany

Contacts

Public ContactRobert Siggel

Uniklinik Köln, Zentrum für Augenheilkunde

robert.siggel@uk-koeln.de0221 478 4313

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026