F32 F33
Conditions
Interventions
Group 1: open label: Treatment with citalopram/escitalopram in standard dosage, additionnally 20 treatments with transcranial direct current stimulation of the left dorsolateral prefrontal cortex in 1
Sponsors
Psychiatrische Klinik
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: depressive syndrome, independent from diagnosis. HAMD>8. informed consent.
Exclusion criteria
Exclusion criteria: gravidity. other severe psychiatric disorder, substance abuse, acute suicidality. brain/skull trauma. Severe neurologic or somatic disease, epilepsy. metal implants in head/neck. Cancer. Intolerability or former loss of efficacy of citalopram/escitlopram.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Primary endpoint is with completion of 20th tDCS, 10 working days after begin of the study. First measurement (baseline) takes place before first stimulation at day 0 with assessment of HAMD. Second measurement (final measurement) takes place after completion of the 20th stimulation with the assessment of the percentual reduction of depression severtiy in the Hamilton Depression Rating Scale (HAMD) | — |
Secondary
| Measure | Time frame |
|---|---|
| Feasability and tolerability of 20 stimulations with the Comfort Rating Questionnaire (CRQ) immediatey after completion of tDCS (20th stimulation, day 10). | — |
Countries
Germany
Contacts
Public ContactUlrich Palm
Psychiatrische Klinik
Outcome results
None listed