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Quantification of Hg excretion and distribution in the biological samples of mercury-amalgam users and its correlation with biological variables

Quantification of Hg excretion and distribution in the biological samples of mercury-amalgam users and its correlation with biological variables - MDA

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
DRKS
Registry ID
DRKS00007944
Enrollment
50
Registered
2015-04-09
Start date
2012-02-05
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

effects of Hg on health of users

Interventions

Group 1: Dental amalgam users: Samples collection and preparation Blood. Blood samples were collected on 1st day, after 6 h of amalgam used, on 3rd day and 12th day from the same person. RBCs and Plas

Sponsors

director Hec scholar ship programme
Lead Sponsor

Eligibility

Sex/Gender
All
Age
24 Years to 68 Years

Inclusion criteria

Inclusion criteria: The study included the subjects used fresh Hg amalgam as the filling material for teeth cavities.

Exclusion criteria

Exclusion criteria: The dental patients used filling material (composite, resin etc.) other than Hg or the individuals exposed to Hg occupationally, environmentally or subjects with old Hg dental filling were excluded from the study

Design outcomes

Primary

MeasureTime frame
mercury was detected in three days 1st, 3rd and 12th day collected biological samples (blood, urine, hair, nails) of dental amalgam users and control (no Hg filling) by analyzing samples through atomic absorption spectrometer. the method "Sakamoto et al., 2010" was used for Hg analysis in biological samples. Hg concentration was found higher in mercury dental amalgam users than non mercury amalgam users in all three times sampling.

Countries

Pakistan

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026