I35.1
Conditions
Interventions
Group 1: A national multicentre, retrospective, risk factor study is proposed. The study design is nonrandomized and non-blinded. This retrospective study will serve as a basis for the establishment o
Sponsors
Universitäts-Herzzentrum Freiburg Bad Krozingen
Eligibility
Sex/Gender
All
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: Patients who underwent one of the variants of the David valve-sparing aortic root replacement procedure as a primary procedure (I-V, intention to treat) with or without the addition of aortic valve cusp and/or commissure repair - Aortic root aneurysm AND/OR - Ascending aortic aneurysm OR - Acute aortic dissection OR - Bicuspid aortic valve OR - Tricuspid aortic valve - Any degree of aortic valve regurgitation - Syndromic patients including Marfan Syndrome, Loeys-Dietz Syndrome, Ehlers-Danlos Syndrome OR - Non-syndromic patients
Exclusion criteria
Exclusion criteria: - More than mild aortic valve stenosis - Aortic valve endocarditis - Reoperation - Redo-Operation - Valve not suitable for valve-sparing operation
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| - Reoperation at five and ten years after the procedure - Aortic valve replacement using a prosthesis five and ten years after the procedure | — |
Secondary
| Measure | Time frame |
|---|---|
| Residual aortic valve regurgitation, progression of aortic valve regurgitation, new onset aortic valve regurgitation, incidence of more than mild / severe aortic valve regurgitation. Time points for all mentioned endpoints is at five and ten years after the primary procedure. | — |
Countries
Germany
Contacts
Public ContactFabian Kari
Universitäts-Herzzentrum Freiburg - Bad Krozingen
Outcome results
None listed