I63.4 I63.0
Conditions
Interventions
Group 1: stroke patients with ischemic infarction (>30% of the territory of the middle cerebral artery)
optimization of MAP>80mmHg
volume substitution or, if necessary, catecholamine (noradrenaline) administration in order to increase MAP >80mmHg
Group 2: stroke patients with ischemic infarction (>30% of the territory of the midd
standard monitoring plus monitoring of cardiac output
optimization of MAP and cardiac output (MAP>80mmHg, cardiac output >3.0 and <4.5)
volume substitution or, if necessary, catecholamine (noradrenaline, dobutamine) administration in order to optimize hemodynamic parameters
Sponsors
Klinik für Neurologie, Universitätsklinikum Freiburg
Eligibility
Sex/Gender
All
Age
18 Years to 85 Years
Inclusion criteria
Inclusion criteria: age >18 or <85years; ischemic infarction via computer tomography or magnetic resonance tomography; =30% of the territory of middle cerebral artery; begin of symptoms <12hours
Exclusion criteria
Exclusion criteria: i.v.-thrombolysis with rtPA; intracerebral hemorrhage; pre-existing disablement according to a modified Rankin score >2; malignant disease
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Clinical outcome after 3 months (modified Rankin Scale) | — |
Secondary
| Measure | Time frame |
|---|---|
| Clinical outcome after 6 months (modified Rankin Scale); in-hospital mortality; length of in-hospital stay; symptomatic cerebral hemorrhage; final infarction volume | — |
Countries
Germany
Contacts
Public ContactHannah Fuhrer
Klinik für Neurologie, Universitätsklinikum Freiburg
Outcome results
None listed