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Peroral Endoscopic Myotomy in Hypercontractile Esophageal motility disorders

Peroral Endoscopic Myotomy in Hypercontractile Esophageal motility disorders - POEM-HYPE

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
DRKS
Registry ID
DRKS00007793
Enrollment
70
Registered
2015-02-11
Start date
2015-03-01
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hypercontractile esophageal motility disorders K22.0

Interventions

Group 1: All consecutive patients with symptomatic achalasia type III and hypercontractile esophageal motility disorders (Chicago classification) receive standardized questionaires, upper GI endoscopy

Sponsors

Medizinische Klinik II, HELIOS Klinikum Krefeld
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: All consecutive recruited achalsia typ III and symptomatic hypercontractile esophageal motility disorders (Chicago Classifikation) vor Eckardt Score > 3 18 – 80 years ASA class 1 and 2

Exclusion criteria

Exclusion criteria: Patients 6cm) Achalasia Type I und II (Chicago Classifikation)

Design outcomes

Primary

MeasureTime frame
Reduction of symptoms of at least 90%, Eckardt score < 3. Symptom reduction is measured by standardized questionaires (SF-36, Eckardt score, visuell-analogue scales) 3 weeks, 6 and 12 month after POEM.

Secondary

MeasureTime frame
Reduction of hypercontractile esophageal motility disordera, DCI < 5000 mmHg-s-cm, < 20% preliminary contractions, reduced DL < 4,5 Sekunden Achalasia Typ III: IRP4 < 10 mmHg or resting pressure lower esophageal sphincter < 5 mmHg These Parameters will be measured by gastrografin swallow, high resolution esophageal manometry and 24h-pH-metry-impedance measurement 3 weeks after POEM.

Countries

Germany

Contacts

Public ContactThomas Frieling

Medizinische Klinik II, HELIOS Klinikum Krefeld

thomas.frieling@helios-kliniken.de02151-322707

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026