F10.2 F10.3
Conditions
Interventions
Group 1: Patients in inpatient qualified withdrawal teatment with Oxazepam p.o., 5-days-scheme (daily dose in brackets):
1. day: 20 – 20 – 20 – 20 + 2 x 20 mg as needed (= 80 + 40 mg)
2. day: 20 – 20
Sponsors
ASKLEPIOS proresearchKlinische Forschung und Entwicklung
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: - Alcohol dependence according to ICD-10 - Minimum age of 18 years - Expected inpatient treatment duration of 20 days - Written informed consent to take part in the study
Exclusion criteria
Exclusion criteria: - Dependence on other substances than alcohol (except nicotine) - Withdrawal treatment according to 5- or 10-days scheme not possible due to mental or somatic comorbidities - Inability to take part in the study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Sum score of AWS scale for the first 5 days. The scale is used to assess vegetative and mental withdrawal symptoms which are rated 4 times a day by the clinic staff. Daily score: 0-116 points, 5-days-sum score: 0-580 points (theoretical limit) | — |
Secondary
| Measure | Time frame |
|---|---|
| - Regular completion of treatment (as documented by the clinic staff) - Course of subjective well-being (well-being questionnaire by von Zerssen, assessed at day 2, 6, 11 and 18) - Course of state anxiety (STAI by Spielberger, assessed at day 2, 11 and 18) - Course of depressive symptoms (BDI by Beck, assessed at day 2, 11 and 18) - Craving for alcohol (VAS, assessed at day 2, 6, 11 and 18) - Satisfaction with treatment (PDQ by Marsden et al., assessed at day 2, 6, 11 and 18) - Course of confidence to stay abstinent (KAZ-35 by Körkel, assessed at day 2, 6, 11 and 18) | — |
Countries
Germany
Contacts
Public ContactUwe Verthein
Zentrum für Interdisziplinäre Suchtforschung der Universität Hamburg (ZIS)Universitätsklinikum Hamburg-Eppendorf, Klinik für Psychiatrie
Outcome results
None listed