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Does manual lymphatic drainage decrease intracerebral pressure? – A pilot study

Does manual lymphatic drainage decrease intracerebral pressure? – A pilot study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
DRKS
Registry ID
DRKS00007648
Enrollment
30
Registered
2015-01-05
Start date
2013-07-01
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

TBI, SAH, ICH, brain tumor, stroke S06 I63 C71 I61

Interventions

Group 1: all patients who are included are treated with manual lymphatic drainage. ICP, CPP, heart frequency and mean arterial pressure are measured 15 minutes before, during and 15 minutes after ther

Sponsors

Klinikum Kassel, Neurologie
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: o acute cerebral disease, o treatment on the Neuro-intensive care unit, Klinikum Kassel, o patient`s with intracranial cerebral monitoring (Neurovent-P, Raumedic AG, Münchberg, Germany), o Intracranial pressure (before therapy) = 18 years

Exclusion criteria

Exclusion criteria: Common exclusion criteria`s for manual lymphatic drainage o congestive heart failure, o acute inflammation (generalized (sepsis) or localized in the head-neck area, o malignant tumor, Furthermore there are those exclusion criteria`s: o missing patient consent, o patient`s age 30mmHg within the last 6 hours, o temperature > 38,5°C within the last 6 hours, o glucose level 500 mg/dl within the last 6 hours, o PH 7,45 within the last 6 hours, o ICP-therapy within the last 6 hours (defined as: Elevation of analgosedation, Osmo-therapy, hypertonic NaCl, ventricular drainage, neurosurgery, TRIS buffer)

Design outcomes

Primary

MeasureTime frame
intracranial pressure (ICP) and cerebral perfusion pressure (CPP), measurements with a device, every minute for 15 minutes before treatment, during manual lymphatic drainage (duration 30 minutes), for 15 minutes after treatment (follow-up period)

Secondary

MeasureTime frame
heart frequency, mean arterial blood pressure Measurements every minute for 15 minutes before treatment, during manual lymphatic drainage (duration 30 minutes), for 15 minutes after treatment (follow-up period)

Countries

Germany

Contacts

Public ContactChristian Roth

Klinikum Kassel, Neurologie

christian.roth@klinikum-kassel.de004956198017219

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026