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Pre- and postoperative evaluation of patient-parameters to investigate the outcome after endothelial keratoplasty

Pre- and postoperative evaluation of patient-parameters to investigate the outcome after endothelial keratoplasty

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
DRKS
Registry ID
DRKS00007566
Enrollment
5000
Registered
2014-12-02
Start date
2013-06-01
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

H18.5 H18.1

Interventions

Group 1: The patients receive regular ophthalmological investigations (visual acuity and visual field testing testing, corneal topography, measurement of the intraocular pressure, dry eye evaluation,

Sponsors

Augenklinik Universität Düsseldorf
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Ability to give informt consent, informt consent to participate in the trial, indication for lamellar keratoplasty

Exclusion criteria

Exclusion criteria: contraindications for endothelial keratoplasty, unability to participate at the follow-up investigations.

Design outcomes

Primary

MeasureTime frame
Functional result (visual acuity testing, Snellen chart), transplant survival (slit lamp investigation). The investigations are performed preoperatively, and 6 weeks, 4-6 months, and 12 months postoperatively, followed by annual investigations in a 10 year follow up.

Secondary

MeasureTime frame
Quality of vision (color vision, visual field testing), corneal status (endothelial cell density, corneal thickness, optical coherence tomography), intraocular pressure (standardised measurement by Goldmann applanation tonometry), development/progression of ocular comorbidities (fundus control, dry eye evaluation, corneal sensitivity measurement). The investigations are performed preoperatively, and 6 weeks, 4-6 months, and 12 months postoperatively, followed by annual investigations in a 10 year follow up.

Countries

Germany

Contacts

Public ContactKristina Spaniol

Augenklinik Universität Düsseldorf

kristina.spaniol@med.uni-duesseldorf.de02118117333

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Mar 2, 2026