Open randomized trial for the comparison of two premedication standards regarding the occurrence of nocturnal respiratory disorders

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00007557

Enrollment

300

Registered

2014-11-27

Start date

2011-01-02

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Sleep-disordered breathing before surgery / anesthesia

Interventions

Group 1: Premedication standard "inpatient surgery" (20 mg clorazepate, each the evening before and the morning before surgery / anesthesia) Group 2: Premedication standard "outpatient surgery" (20 mg

Eligibility

Sex/Gender

All

Age

18 Years to 80 Years

Inclusion criteria

Inclusion criteria: Patients between 18 and 80 years before scheduled surgery

Exclusion criteria

Exclusion criteria: Severe infectious disease, severe mental diesease, pregnancy, inability to consent

Design outcomes

Secondary

Measure	Time frame
Comparison of patient's stress level in regard of the premedication standard. Analysis via saliva cortisol the morning before surgery.	—

Primary

Measure	Time frame
Analysis of sleep-disordered breathing in regard of the randomized premedication standard via polygraphy during the preoperative night.	—

Countries

Germany

Contacts

Public ContactFrank Dette

Universitätsmedizin Mainz; Klinik für Anästhesiologie

Frank.Dette@web.de06131-176755

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026