The influence of appetit and volumregulating peptides on alcohol craving in alcohol dependent patients

The influence of appetit and volumregulating peptides on alcohol craving in alcohol dependent patients - AllCuP

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00007532

Enrollment

Registered

2017-05-17

Start date

2014-12-01

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

F10.2

Interventions

Group 1: Alcohol addicted patients in the intervention group with a forced water intake of 1000 ml still mineral water in 10 minutes. Group 2: Alcohol addicted patients in thecontrol group without a

Eligibility

Sex/Gender

Male

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: - age between 18 and 65 years, - male gender - Patients of the intervention group and control group I: diagnoses of an alcohol addiction according to ICD 10 and DSM IV - sufficient ability to communicate with the study employee, to answer questions respective questionnaires. - Fully Informed Consent) - Written Informed Consent).

Exclusion criteria

Exclusion criteria: - female gender - axis I diagnosis according to ICD 10 and DSM IV except for a nicotine addiction or abuse (as well as alcohol addiction in the intervention group and control group I - Actual psychotrope medication - internistic diseases, which were contraindications for the forced volume intake - For the alcohol addicted patients: grand mal during detoxification and a delirium tremens - for healty controls: abuse or addiction of alcohol - suicidal tendency and endangerment of others. - drug addiction or abuse except for nictoine

Design outcomes

Primary

Measure	Time frame
Changes in alcohol craving after a forced volume intake measured by a visual analog scale 10, 20, 30, 40, 50, 60, 75, 90 and 120 minutes after an alcohol cue exposure session.	—

Secondary

Measure	Time frame
Comparison of the association between the alcohol craving and plasma concentrations of ghrelin, ANP, argenine vasopressin and leptin between the intervention group and the control group I at 10, 20, 30, 40, 50, 60, 75, 90 and 120 minutes after the alcohol cue exposure session.	—

Countries

Germany

Contacts

Public ContactAnne Koopmann

Zentralinstitut für Seelische Gesundheit Klinik für Abhängiges Verhalten und Suchtmeidzin

anne.koopmann@zi-mannheim.de0621/1703-3721

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026