E10
Conditions
Interventions
Group 1: Determination of T cell response (FACS analysis) in patients with diabetes manifestation and age of manifestation below 5 years. Correlation of the results with data from the patients health
age 5 to 18. Correlation of the results with data from the patients health record and with metabolic parameters.
Group 4: Determination of T cell response (FACS analysis) in patients without diabete
age 5 to 18. Correlation of the results with data from the patients health record and with metabolic parameters.
Sponsors
Universitätklinikum Düsseldorf Klinik für Allgemeine Pädiatrie, Kinderkardiologie und Neonatologie
Eligibility
Sex/Gender
All
Age
0 Years to 18 Years
Inclusion criteria
Inclusion criteria: type 1 diabetes; at manifestation or with diabetes duration of at least one year; age 0-18
Exclusion criteria
Exclusion criteria: acute infection
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Differences in the T cell response depending on age at manifestation, duration of diabetes, metabolic parameters. What: T cell response, isolation of micro RNA, data from the patient's health record, metabolic parameters When: one study appointment (arm 3 and 4), two study appointments (arm 1 and 2); second visit 6 to 12 weeks after first visit How: Flow cytometry | — |
Secondary
| Measure | Time frame |
|---|---|
| Differences in the T cell response depending on clinical parameters. What: T cell response, isolation of micro RNA, data from the patient's health record, metabolic parameters When: one study appointment (arm 3 and 4), two study appointments (arm 1 and 2) How: Flow cytometry | — |
Countries
Germany
Contacts
Public ContactKatharina Förtsch
Universitätklinikum Düsseldorf, Klinik für Allgemeine Pädiatrie, Kinderkardiologie und Neonatologie
Outcome results
None listed