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The General Weakness Syndrom Therapy (GymNAST) study: A cohort study on recovery on walking function.

The General Weakness Syndrom Therapy (GymNAST) study: A cohort study on recovery on walking function. - GymNAST

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
DRKS
Registry ID
DRKS00007181
Enrollment
150
Registered
2014-11-12
Start date
2013-06-03
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

G62.80 G72.80

Interventions

Group 1: Biweekly evaluation of motor and cognitive functions in patients with ICUAW from admission to the early rehabilitation and weaning centre till discharge. Further measurment of quality of life

Sponsors

Klinik Bavaria
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 85 Years

Inclusion criteria

Inclusion criteria: Patient is chronic critical ill or has a contemporary history of chronic critical ill; Defined diagnosis of CIM and CIP; muscle weakness defined as a Medical Research Council (MRC) sum score of less than 48 points; Richmond Agitation-Sedation Scale (RASS) score from -1 to +2; written informed consent of the patient

Exclusion criteria

Exclusion criteria: Patients receiving palliative care; comorbidities of the trunk or the lower limbs interfering with upright posture and walking function (eg, amputation or fracture of lower limb); other neuromuscular or neurological disease and/or syndromes causing weakness in patients in the ICU; Severe physical comorbidity before becoming critical ill

Design outcomes

Primary

MeasureTime frame
daily measuring of walking ability (Functional Ambulation Category) and sit to stand (ability to stand up from a standardized chair) from admission to the early rehabilitation and weaning centre until discharge

Secondary

MeasureTime frame
motor functions and activity (MRC-Powerscale, FSS-ICU, PFIT-s, gripstrengh, Frühreha-Barthel-Index, 10M-Walking Test, 6Min-Walking Test, FAC), cognition (CDT, MoCA), quality of life (EQ-5D, RNL-I), activities of daily living (PASIPD, Barthel-Index) biweekly from admission to the cetre for early rehabilitation (T0, T1 after 2 weeks, T2 after 4 weeks etc.) until discharge

Countries

Germany

Contacts

Public ContactSimone Mückel

Erste Private Europäische Medizinische Akademie für Rehabilitation

simone.mueckel@klinik-bavaria.de035206-62132

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Mar 3, 2026