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Noninterventional study on the administration of Spasmex® 45 mg coated tablets in elderly female and male patients suffering from symptoms of urge in daily urological practice - a noninterventional study with epidemiological aspects

Noninterventional study on the administration of Spasmex® 45 mg coated tablets in elderly female and male patients suffering from symptoms of urge in daily urological practice - a noninterventional study with epidemiological aspects - NIS-056

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
DRKS
Registry ID
DRKS00007109
Enrollment
1250
Registered
2014-10-29
Start date
2014-11-03
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

MedDRA - LLT,10059617:overactive bladder N32.8

Interventions

Group 1: There is only one treatment arm. There are 3 visits per patient. The period of time between the visits corresponds to the general practice. A period of time of at least 10 days between the vi

Sponsors

Dr. R. Pfleger GmbH
Lead Sponsor

Eligibility

Sex/Gender
All
Age
65 Years to No maximum

Inclusion criteria

Inclusion criteria: at least 65 years of age; symptoms of overactive bladder; prescription of Spasmex 45mg coated tablets

Exclusion criteria

Exclusion criteria: younger than 65 years of age

Design outcomes

Primary

MeasureTime frame
a) to determine the anticholinergic burden caused by drugs using the total score of Anticholinergic Cognitive Burden Scale (ACBS) on visit 1, 2 and 3 b) to determine and quantify the morbidity using the Cumulative Illness Rating Scale for Geriatrics (CIRS-G) on visit 1 c) to detemine the efficacy using the following parameters: - number of micturitions per day (on visit 1, 2 and 3) - intensity of urgency (on visit 1, 2 and 3) - incontinence episodes (on visit 1, 2 and 3) - overall assessment of efficacy by patient and by physician (on visit 2 and 3) d) to determine the divisibility of the coated tablets using an ordinal scale (on visit 3) e) overall assessment of tolerability by patient and by physician (on visit 2 and 3) f) documentation of side effects (on visit 2 and 3) A period of time of at least 10 days between the visits is recommended.

Secondary

MeasureTime frame
See Primary outcome. In this noninterventional study there are no primary or secondary endpoints. All variables will be evaluated descriptively. No hypothesis will be tested, no comparison of different populations will be done.

Countries

Germany

Contacts

Public ContactClaudia Neumeister

Dr. R. Pfleger GmbH

nis-056@dr-pfleger.de0951/6043-0

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Mar 5, 2026