Specificity of the saliva cortisol measurements in patients with obesity and development of a weight-dependent threshold value for the saliva cortisol for obese patients with a BMI > 35 for better early detection of Cushingsyndroms

Specificity of the saliva cortisol measurements in patients with obesity and development of a weight-dependent threshold value for the saliva cortisol for obese patients with a BMI > 35 for better early detection of Cushingsyndroms - Salivary cortisol study

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00006826

Enrollment

367

Registered

2015-05-15

Start date

2014-05-10

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

E66 E24

Interventions

Group 1: At study entry , the enclosure of 2 tubes saliva occurs . These are filled in a home environment on 2 subsequent days by 22 clock according to instructions with saliva and sent by post. If th

Eligibility

Sex/Gender

All

Age

18 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1. Age : 18-60 years ( and the capacity to consent ) 2. Patients with grade III obesity i.e . BMI = 35 kg / m²

Exclusion criteria

Exclusion criteria: 1. pregnancy 2. Current or recent previous history of use of cortisone preparations ( inhalants , topical , tablets, injections) 3. Shift work 4. Acute infection 5. Severe hepatic and renal insufficiency and heart failure 6. chewing tobacco consume 7. taking phenytoin, barbiturates , loperamide, opioids

Design outcomes

Primary

Measure	Time frame
Investigation of the specificity and (sensitivity ) of salivary cortisol measurement in obesity patients to determine a weight specific cortisol level	—

Countries

Germany

Contacts

Public ContactClarissa Schulze zur Wiesch

III. Medizinische Klinik, Sektion Diabetologie und Endokrinologie, UKE

cl.schulze-zur-wiesch@uke.de040-7410-51473

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026