Interventional study to optimize the preventive behavior in first-degree relatives of patients with colorectal carcinoma

Interventional study to optimize the preventive behavior in first-degree relatives of patients with colorectal carcinoma - SAPHIR

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00006818

Enrollment

316

Registered

2014-11-10

Start date

2014-06-04

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Colorectal carcinoma (CRC) prevention, the preventive behavior in first-degree relatives C26.0

Interventions

Group 1: Interventional (133) Planned sample size 266 (R 1:1) The patients of the intervention group (1. arm) receive intensive training in order to qualify them to communicate their knowledge about t

Eligibility

Sex/Gender

All

Age

18 Years to 90 Years

Inclusion criteria

Inclusion criteria: - Patients are diagnosed with colorectal cancer who have relatives - Existence of the consent of personal data - Diagnosis max 6 months 1) Histologically confirmed CRC 2) Patients must be 18 years of age. 3) Patients must be able to understand the investigational nature of this study and give written informed consent prior to study entry.

Exclusion criteria

Exclusion criteria: severe mental illness

Design outcomes

Primary

Measure	Time frame
Participation rate of preventive colonoscopy of first-degree relatives six months after intervention; economic efficiency of the training measure of affected patients to improve the preventive behavior of the risk group.	—

Secondary

Measure	Time frame
Detect the potential of colorectal cancer patients to act as communicators because they are considered to be particularly suited to support preventive measures due to their knowledge of the consequences of the disease and their family ties. The target of this quantitative approach is a significant increase of the acceptance of prevention in the family environment. Feasibility and implementation of the intervention measure. ? Analysis of economic efficiency. Costs of training and preventive colonoscopies are to be compared with the avoided medical and economic follow-up costs. Attitude of the relatives towards the intervention of their family member to motivate them for colonoscopy. A qualitative approach examines the motivation of selected families and the chances of the intervention measure. Modeling of the reduction rate of colorectal cancer in the concerned families according to the acceptance of preventive colonoscopy based on the collected data to find out the efficacy of this preventive measure.	—

Measure

Time frame

Detect the potential of colorectal cancer patients to act as communicators because they are considered to be particularly suited to support preventive measures due to their knowledge of the consequences of the disease and their family ties. The target of this quantitative approach is a significant increase of the acceptance of prevention in the family environment. Feasibility and implementation of the intervention measure. ? Analysis of economic efficiency. Costs of training and preventive colonoscopies are to be compared with the avoided medical and economic follow-up costs. Attitude of the relatives towards the intervention of their family member to motivate them for colonoscopy. A qualitative approach examines the motivation of selected families and the chances of the intervention measure. Modeling of the reduction rate of colorectal cancer in the concerned families according to the acceptance of preventive colonoscopy based on the collected data to find out the efficacy of this preventive measure.

—

Countries

Germany

Contacts

Public ContactFabian Frielitz

Medizinische Klinik II,Onkologie / Hämatologie und Sektion Pneumologie,Hubertus Wald Tumorzentrum,Universitäres Cancer Center (UCCH),Universitätsklinikum Eppendorf

f.frielitz@uke.de016304808000

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026