Pregnancy, Hypotension, spinal anesthesia, Cesarean section, Coloading, coload, crystalloids, colloids, vasopressors I95.2
Conditions
Interventions
Group 1: Coloading with Crystalloid Infusion 1000ml during Spinal Anaesthesia for elective Sectio Caesarea. ( current clinic Standard).
Group 2: historic collective population: coloading with HAES 6%
Sponsors
Charité Campus Virchow-Klinikum
Eligibility
Sex/Gender
Female
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: -ASA II-III -Age > 18 -Elective Sectio caesarea -Consensus Statement at least 24h before the OP start. -Ability to consent
Exclusion criteria
Exclusion criteria: -Patient refusal to participate in the study or to receive regional Anesthesia -Inability of legal competence -Insufficient German knowledge -Pregnancy complications ( known Hypertension, HELLP Syndrom, Eclampsia ) - <28 Pregnancy week. - chronic Pain - Alcohol, Painkillers, Drug- Abusion - psychiatric Disorders (Depression, Psychosis), Medikation with Psychopharmaka - Stillbirth -Allergy to Local Anaesthetics - Coagulopathy (acquired, induced, genetic) als contraindication for Spinal Anaesthesia -Participation in other Studies ( one month before or three months after planned study participation) - Involuntary commitment of the Patient
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary end point is the difference between baseline systolic pressure and the lowest systolic pressure after Coloading/ SpA. | — |
Secondary
| Measure | Time frame |
|---|---|
| Incidence of hypotension Vasopressors requirements (ml) (Cafedrin-Theoadrenalin / Phenylephrin), intraop. crystalloids requirements (ml) Estimated blood loss (ml) umbilical artery pH, Apgar score | — |
Countries
Germany
Contacts
Public ContactLutz Kaufner
Charité Campus Virchow-Klinikum, Klinik für Anästhesiologie mit Schwerpunkt operative Intensivmedizin
Outcome results
None listed