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Evaluation of clinical, neurophysiological and imaging parameter to detect and characterize chronic central neuropathic pain after spinal cord injury

Evaluation of clinical, neurophysiological and imaging parameter to detect and characterize chronic central neuropathic pain after spinal cord injury

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
DRKS
Registry ID
DRKS00006779
Enrollment
36
Registered
2014-09-23
Start date
2014-05-19
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

G82.4 M79.2

Interventions

Group 1: Evaluation of 12 healthy subjects (once) by means of pain questionnaires, psychometric tests, electrophysiological examinations (H-reflex, flexor-reflex, LEP, SSEP), quantitative sensory test
before and after sensorimotor activation) by means of pain questionnaires, psychometric tests, electrophysiological examinations (H-reflex, flexor-reflex, LEP, SSEP), quantitative sensory testing and

Sponsors

Klinik für Paraplegiologie,Universitätsklinikum Heidelberg
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Able to consent; chronic spinal cord injury at least 12 months post injury; neurological Level of injury C5 to Th10

Exclusion criteria

Exclusion criteria: Sensory impairment in dermatome C2 on both sides; artificial respiration; cauda-equina syndrome; epilepsy; impaired cognitive ablilities; pre-existing mental disorder; cardiac pacemaker; other active implants (e.g. phrenic pacemaker, drug pumps); metal implants less than 20 cm away from electrodes for electrical stimulation; severe traumatic brain injury in clinical history; pre-existing sensory deficits or dieseases which entail polyneuropathy (e.g. diabetes mellitus); severe primary internistic diseases (e.g. oncological, cardilogical); pregnancy.

Design outcomes

Primary

MeasureTime frame
Detection of neuropathic pain in chronic spinal cord injured patients by means of pain questionnaires and subsequent evaluation of findings from (1) Quantitative Sensory Testing/clinical examination, (2) H-Reflex/flexor-reflex/LEP/SSEP and (3) magnetic resonance imaging (VBM) compared to findings from the same methods in chronic spinal cord injured patients without neuropathic pain and healthy subjects.

Secondary

MeasureTime frame
Influenceability of these parameters by sensorimotor activation.

Countries

Germany

Contacts

Public ContactSteffen Franz

Klinik für Paraplegiologie, Universitätsklinikum Heidelberg

steffen.franz@med.uni-heidelberg.de+4962215626322

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 9, 2026