Analysis for changing the arterial-to-end-tidal CO2 difference under pneumoperitoneum (PP)

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00006731

Enrollment

Registered

2014-09-16

Start date

2014-12-02

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Laparoscopic operation

Interventions

Group 1: 1. Determination of arterial CO2 content by arterial blood gas analysis at various time points - After induction of anesthesia - Before performing a recruitment maneuver (RM), - After complet

Eligibility

Sex/Gender

All

Age

18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Age: 18 - 75 years 2. Gender: male and female 3. race: caucasian 4. Body weight: BMI from 18 5. patients undergoing clinically indicated laparoscopic surgery 6. assent to necessary measures (arterial access or arterial puncture) with the written consent

Exclusion criteria

Exclusion criteria: 1. reduced lung function (FEV1 / VC <70% and FEV1 <80%) 2. COPD, Z.n. Status asthmaticus 3. Third right-to-left shunt or left-to-right shunt 4. pneumonia, pulmonary edema or state after pulmonary embolism 5. interstitial lung diseases 6. large pleural effusions 7. heart failure (NYHA III and IV) 8. systolic blood pressure <100 mmHg and diastolic <50 mmHg, volume depletion 9. decompensated liver or kidney disease 10. infection within the last 14 days 11. Contraindications to arterial access or arterial puncture (eg Allen test) 12. Refusal to participate in the study by the patient

Design outcomes

Primary

Measure	Time frame
The aim of this study is to investigate whether, after creating a pneumoperitoneum during laparoscopic surgery an increase in the arterial-to-end-tidal CO2 concentration was recorded 1. Determination of arterial CO2 content by arterial blood gas analysis at various time points - After induction of anesthesia - Before performing a recruitment maneuver (RM), - After completion of the RM - Before induction of PP, - Immediately after induction of PP and - During which time in 30 minute intervals - Once after completion of the PP	—

Measure

Time frame

The aim of this study is to investigate whether, after creating a pneumoperitoneum during laparoscopic surgery an increase in the arterial-to-end-tidal CO2 concentration was recorded 1. Determination of arterial CO2 content by arterial blood gas analysis at various time points - After induction of anesthesia - Before performing a recruitment maneuver (RM), - After completion of the RM - Before induction of PP, - Immediately after induction of PP and - During which time in 30 minute intervals - Once after completion of the PP

—

Secondary

Measure	Time frame
Occur Study about the occurrence of differences in the range of the CO2 difference between patients with normal weight, overweight and obese	—

Countries

Germany

Contacts

Public ContactChristof Maria Strang

Klinik für Anästhesiologie und IntensivtherapieUniversitätsklinikum Magdeburg

christof.strang@med.ovgu.de0391-67-13500

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026