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“Multimodal physiotherapy as an add-on treatment to botulinum toxin type A therapy in patients with cervical dystonia: a pilot trial”

“Multimodal physiotherapy as an add-on treatment to botulinum toxin type A therapy in patients with cervical dystonia: a pilot trial” - Dys-PT

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
DRKS
Registry ID
DRKS00006562
Enrollment
20
Registered
2014-09-16
Start date
2014-10-22
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

G24

Interventions

Group 1: The study is divided in two phases, each with three months' duration. Within the first phase the usual BTX application will be performed. Furthermore the baseline values are collected and the

Sponsors

Universitätsklinikum Jena, Institut f. Physiotherapie
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: - Cervical dystonia diagnosed - Continuous treatment with botulinumtoxin in an three months interval - At least one year treatment with botulinumtoxin

Exclusion criteria

Exclusion criteria: - Contraindications for the physiotherapy treatment - Contraindications for the botulinumtoxin treatment - Refusal of the study participation

Design outcomes

Primary

MeasureTime frame
Main object of this study is to validate the effectiveness of a multimodal PT program as an additional therapy to BTX injection versus BTX application alone. Primary objectives are the quality of life determined by the SF-36 score and the mobility of the cervical spine which will be detected by the measuring system ZEBRIS. These assessments will be collected at the beginning and repeated at an interval of six weeks until the end of the study.

Secondary

MeasureTime frame
Secondary object is the Toronto Western Spasmodic Rating Scale (TWSTRS) which includes severity, disability and pain of the cervical dystonia. Another secondary variable is the electrical activity from the concerned muscles measured by an surface electromyography. These assessments will be collected at the beginning and repeated at an interval of six weeks until the end of the study.

Countries

Germany

Contacts

Public ContactA. Günther

Uniklinikum Jena, Hans-Berger-Klinik für Neurologie

albrecht.guenther@med.uni-jena.de03641/9 323450

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Mar 4, 2026