Prevalence and risk factors of delirium in elderly patients in a university hospital

Prevalence and risk factors of delirium in elderly patients in a university hospital - PRE-DELIR

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00006545

Enrollment

550

Registered

2014-07-30

Start date

2014-10-14

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

F05 F09 F03

Interventions

Group 1: In-patients of the University Hospital Jena aged 60 and older will be assessed using standardized scores for delirium, its major risk factors and presence of dementia. After 6 months, patient

Eligibility

Sex/Gender

All

Age

60 Years to No maximum

Inclusion criteria

Inclusion criteria: Necessity of in-patient care in a department of the university medical center

Exclusion criteria

Exclusion criteria: in-patients of the psychiatric clinic

Design outcomes

Primary

Measure	Time frame
In this study, all in-patients of the University Hospital Jena aged 60 years and older will be included. They will be examined in a standardized assessment for delirium and its risk factors as well as for dementia. In a one day survey, general data of the patients and the current hospital stay will be collected. Alertness will be assessed by the Richmond Agitation and Sedation Scale (RASS), patients with delirium will be identified by the Confusion Assessment Method (CAM) on general wards and by the CAM-ICU in intensive care units.	—

Measure

Time frame

In this study, all in-patients of the University Hospital Jena aged 60 years and older will be included. They will be examined in a standardized assessment for delirium and its risk factors as well as for dementia. In a one day survey, general data of the patients and the current hospital stay will be collected. Alertness will be assessed by the Richmond Agitation and Sedation Scale (RASS), patients with delirium will be identified by the Confusion Assessment Method (CAM) on general wards and by the CAM-ICU in intensive care units.

—

Secondary

Measure	Time frame
For determination of risk factors for delirium, following parameters will be investigated within the one day survey: presence of infection, creatinin elevation, derangement of electrolytes or blood sugar level, existence of an urethral catheter. Furthermore, the following scores will be used: Identification of Seniors at Risk (ISAR) for general risk factors for a worse outcome, Montreal Cognitive Assessment (MoCA) for cognitive performance, SOF-Frailty-Index (Study of Osteoporotic Fractures) to determine frailty and the chair rising test to determine mobility. The one day survey will be followed by an interview of the patients’ relatives with the Informant Questionnaire on Cognitive Decline in the Elderly (IQCODE) as an external judgement of the cognitive performance to be able to differentiate between delirium and dementia. In an outcome-suryey 6 months after initial assessment, the current living conditions, the independence and the state of health will be determined via the Karnofsky-Index and the European Quality of Life 5 Dimensions-Score (EQ-5D) completed with a cognitive dimension (EQ-6D). For up to two years after the first contact, mortality of the patients will be determined, including the exact date of death.	—

Measure

Time frame

For determination of risk factors for delirium, following parameters will be investigated within the one day survey: presence of infection, creatinin elevation, derangement of electrolytes or blood sugar level, existence of an urethral catheter. Furthermore, the following scores will be used: Identification of Seniors at Risk (ISAR) for general risk factors for a worse outcome, Montreal Cognitive Assessment (MoCA) for cognitive performance, SOF-Frailty-Index (Study of Osteoporotic Fractures) to determine frailty and the chair rising test to determine mobility. The one day survey will be followed by an interview of the patients’ relatives with the Informant Questionnaire on Cognitive Decline in the Elderly (IQCODE) as an external judgement of the cognitive performance to be able to differentiate between delirium and dementia. In an outcome-suryey 6 months after initial assessment, the current living conditions, the independence and the state of health will be determined via the Karnofsky-Index and the European Quality of Life 5 Dimensions-Score (EQ-5D) completed with a cognitive dimension (EQ-6D). For up to two years after the first contact, mortality of the patients will be determined, including the exact date of death.

—

Countries

Germany

Contacts

Public ContactHannah Zipprich

Universitätsklinikum Jena Hans-Berger-Klinik für Neurologie

hannah.zipprich@med.uni-jena.de+4936419323429

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026