No specific diseases will be studied. This is a study with healthy controls.
Conditions
Interventions
Group 1: Non-interventional observational study: cognitive tests, behavioral tests, questionnaires and interviews with parents and child, stress hormones in saliva and urine, epigenetic testing in sal
Sponsors
Zentralinstitut für Seelische Gesundheit
Eligibility
Sex/Gender
All
Age
38 Months to 46 Months
Inclusion criteria
Inclusion criteria: Participation in our previous POSEIDON study. For new recruitments: living in the Mannheim area, german language, parental capacity to consent
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| impaired neuropsychological development (Developmental NEuroPSYological assessment) and psychopathology (Childhood Behavior Checklist, CBCL): one measure at the age of approx 38 months | — |
Secondary
| Measure | Time frame |
|---|---|
| Activation of stress-responsive systems (cortisol in morning urine and saliva); differential methylation of specific stress-related genes; behavior in psychological tests (Strange Situation Task, Delayed Gratification Task); brain development (magnetic resonance imaging: "resting state", diffusion tensor imaging, volumometry) | — |
Countries
Germany
Contacts
Public ContactMichael Deuschle
Zentralinstitut für Seelische Gesundheit
Outcome results
None listed