Postoperative volumetry after hippocampus-sparing epilepsy surgery

Postoperative volumetry after hippocampus-sparing epilepsy surgery - VBM-HipSpare

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00006313

Enrollment

100

Registered

2014-07-11

Start date

2014-07-14

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

G40.2 G40.3

Interventions

Group 1: Hippocampus spared: pre-/postoperative volumetry of the spared hippocampus to detect a volumetric difference between timepoints

correlation of neuropsychological surrogate markers pre-/postoperative with the hippocampal volume (post-op: 3 months) Group 2: Anterior temporal lobectomy (control 1): Group-wise comparison of postop

Eligibility

Sex/Gender

All

Age

16 Years to 65 Years

Inclusion criteria

Inclusion criteria: Epilepsy surgery within the temporal lobe sparing the hippocampus

Exclusion criteria

Exclusion criteria: Missing postoperative MRI data, dual pathology on MRI scan

Design outcomes

Primary

Measure	Time frame
Volumetric difference between preoperative and postoperative hippocampus volumes, assessment via voxel-based morphometry three months after surgery	—

Secondary

Measure	Time frame
Links between loss of hippocampal volume and neuropsychological deficits, effect of the resection volume on postoperative hippocampal volume loss, evaluation three months after surgery	—

Countries

Germany

Contacts

Public ContactNiels Foit

Uniklinik Freiburg

niels.foit@uniklinik-freiburg.de+4976127052230

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026