postoperative pneumocephalus
Conditions
Interventions
Group 1: Patients randomized to the treatment arm will be ventilated with FiO2 = 100% at 1.0 ATA via the ETT for a period of 3 hours, starting immediately after their admission to the neurosurgical IC
Sponsors
Medizinische Hochschule Hannover
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: - Patient’s age above 18 years - Surgery with standard anaesthetic and ventilation procedures - Postoperative course must be uneventful without any complication. - CT scan show intracranial air collection of 30 ml or more.
Exclusion criteria
Exclusion criteria: - Patients with a history of any cardiac disease or previously cardiac surgery, any pulmonary disease, chronic obstructive pulmonary disease (COPD), chronic cough or dyspnoe, abnormal chest X-ray, or previously pulmonary surgery - Patients, who will need, for whatever reason, a CSF drain or prolonged postoperative ventilation - Pregnant or breastfeeding women
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. The mean change of air volume between CT scan performed immediately and 24 hours after completion of surgery. 2. The air resorption rate (the mean change of air volume / hour). | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Attention at 24 hours after completion of surgery: Stroop color-word interference tests 2. Alertness at 24 hours after completion of surgery: Stanford Sleepiness Scale | — |
Countries
Germany
Contacts
Public ContactBujung Hong
Klinik für Neurochirurgie Medizinische Hochschule Hannover
Outcome results
None listed