Decrease of incidence of postoperative delirium by optimizing orientation stimuli in cardiosurgery patients of an intensive care unit. A trial using the CAM-ICU

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00006217

Enrollment

220

Registered

2014-06-05

Start date

2014-06-01

Completion date

Unknown

Last updated

2025-10-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

F05 F43.1

Interventions

Group 1: In addition to treatment as usual this group (n=110) receives additional stimuli which activate reality (acustic, visual, olfactorical and tactile stimuli). Stimuli are given twice a day in t

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: elective cardiosurgery with a recovery period at the intensive care unit

Exclusion criteria

Exclusion criteria: missing consent to participate; not familiar with German language; prior diagnosis of an delirium; psychiatric diagnosis of schizophrenia; hints of cognitive dysfunction prior to surgery (AMT-score <7), RASS-score <-2 at testing day at the ICU

Design outcomes

Primary

Measure	Time frame
Incidence of postoperative delirium diagnosed by CAM-ICU. CAM-ICU is conducted twice a day at the first three days after surgery.	—

Secondary

Measure	Time frame
anxiety; pain; developement of a posttraumatic stress disorder (PTSS-14); quality of life after surgery (SF-12); AChE; BChE; Nu-DESC (Delirium). Time of measurements: 1st, 2nd, 3rd day after surgery (daily twice): NRS (anxiety,; pain), Nu-DESC, AChe, BChe. In addition CAM-ICU by another staff member who is blinded with respect to the experimental condition. Three months after surgery: SF-12 and PTSS-14.	—

Measure

Time frame

anxiety; pain; developement of a posttraumatic stress disorder (PTSS-14); quality of life after surgery (SF-12); AChE; BChE; Nu-DESC (Delirium). Time of measurements: 1st, 2nd, 3rd day after surgery (daily twice): NRS (anxiety,; pain), Nu-DESC, AChe, BChe. In addition CAM-ICU by another staff member who is blinded with respect to the experimental condition. Three months after surgery: SF-12 and PTSS-14.

—

Countries

Germany

Contacts

Public ContactMichael Hüppe

Universität zu Lübeck, Klinik für Anästhesiologie und Intensivmedizin

michael.hueppe@uni-luebeck.de0451 - 5006214

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 26, 2026