Infection and Reactivation of HCMV and other Herpesviridae in children with neutropenic fever after chemotherapy

Infection and Reactivation of HCMV and other Herpesviridae in children with neutropenic fever after chemotherapy - CMV-FiZ

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00006152

Enrollment

140

Registered

2014-05-09

Start date

2014-05-15

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

malignant disease, neutropenic fever. C00-C97

Interventions

Group 1: patients with neutropenic fever, analysis of CMV, EBV, HSV and CMV reactivation

Eligibility

Sex/Gender

All

Age

No minimum to 19 Years

Inclusion criteria

Inclusion criteria: Chemotherapy due to malignant disease. Initial Diagnosis in local center.

Exclusion criteria

Exclusion criteria: BMT. Missing informed consent.

Design outcomes

Primary

Measure	Time frame
CMV Reactivation in neutropenic Fever (analysis of CMV DNA, analysis of activation of HCMV MIEP promotor through patient serum)	—

Secondary

Measure	Time frame
Frequency of miscellaneous infections in neutropenic fever	—

Countries

Germany

Contacts

Public ContactMartin Knorr

Universitätskinderklinik Essen, Pädiatrische Hämatologie/Onkologie

martin.knorr@uk-essen.de0201-723-2255

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026