TESD Pilot study - TEM vs. ESD

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00006125

Enrollment

Registered

2014-05-05

Start date

2014-05-10

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

D12.8 C20

Interventions

Group 1: Transanal endoscopic microsurgery (TEM) Group 2: Endoscopic submucosal dissection (ESD)

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Non-pedunculated adenomas of the rectum > 15mm, < 40% of the circumference Low-risk rectum carcinoma Randomizable in regard to TEO or ESD (ventral up to 10 cm a.a., dorsal up to 14 cm a.a.)

Exclusion criteria

Exclusion criteria: Recurrence after malignoma Other malginant tumors Ulcerative colitis, FAP, HNPCC Patient without possibility for written consent

Design outcomes

Primary

Measure	Time frame
Recurrence after 12 month	—

Secondary

Measure	Time frame
Rate of en-bloc-resection Rate of R0-resection Hospital stay Complications (Clavien) Quality of life (GIQLI) and incontinence (Wexner) by questionnaire preoperative and 3, 6 and 12 month postoperative.	—

Countries

Germany

Contacts

Public ContactMoritz Sold

Universitätsmedizin MannheimZentrale Interdisziplinäre Endoskopie

moritz.sold@web.de0621 - 3832625

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026