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fMRI in the KIDS-WIN-study: Neural correlates of a working memory and a self-regulation training in schoolchildren

fMRI in the KIDS-WIN-study: Neural correlates of a working memory and a self-regulation training in schoolchildren - fMRI Kids-Win

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
DRKS
Registry ID
DRKS00006082
Enrollment
250
Registered
2014-04-16
Start date
2014-04-15
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy children

Interventions

Group 1: Working Memory Training: Treatment • In each class students are randomly assigned into a treatment and a control group. • Treatment group: Software for WM-training: RoboMemo from Cogmed aims
has an interface specifically designed for school age children
is available in German. Implementation: 25 training sessions (30-45 min, 8 exercises, 1 session/workday). Total duration of the program: 5 weeks. Group 2: Working Memory Training: • Control group: a

Sponsors

Universität Zürich
Lead Sponsor

Eligibility

Sex/Gender
All
Age
5 Years to 9 Years

Inclusion criteria

Inclusion criteria: All subjects will be physically and psychologically healthy, as ascertained by standard interviews prior to testing. Participants must be between 5 and 9 years of age and take part in the behavioral KIDS-WIN-study. Moreover, none of the exclusion criteria can apply to the participant.

Exclusion criteria

Exclusion criteria: In line with established safety guidelines, participants must meet the safety criteria for fMRI. Any child with internal electronic and/or metallic objects (e.g. braces, artificial cochleae, medical pumps, shrapnell, metallic splinters due to accidents during metal welding, cardiac pacemaker, deep brain neurostimulator, etc.) will be excluded from participation. Also, children with Claustrophobia, a diagnosis of psychiatric or neurologic disorder, brain trauma or injury, and left handed children will be excluded from the study.

Design outcomes

Primary

MeasureTime frame
The primary outcome of the study will be the changes of the Blood Oxygen Level Dependent signal (BOLD) during the different training conditions as well as T1 and diffusion weighted images to identify changes in volume of grey and white matter substance. Such measures will be taken at a baseline point (before the start of the training programs) and once the training programs have been finished (maximum delay between end of program and scanning session will be 24 months).

Secondary

MeasureTime frame
Behavioural performance differences during the different tasks performed inside and outside the scanner, which will be recorded on each scanning session. The main performance measures vary between the different tasks, but typically all of them include measures of accuracy (% of correct responses), mean reaction time and variability of their responses. The tasks are programmed using Psychtoolbox (psychtoolbox.org), and the scripts used include the recording of all the responses of the participant.

Countries

Switzerland

Contacts

Public ContactTodd A Hare

Universität Zürich

todd.hare@econ.uzh.ch+41 44 634 10 17

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026