Impact of a nitrous oxide / oxygen mixture (LIVOPAN) on pain intensity during photodynamic therapy – an observational study (LIVOPAN-trial)

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00006054

Enrollment

Registered

2015-01-05

Start date

2014-08-01

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

R52.0 L57.0

Interventions

Group 1: Patients experiencing a severe pain of VAS= 6 during the first PDT of one cheek, in spite of oral analgesia, will be offered oral analgesics and an additional LIVOPAN - analgesia (nitrous oxi

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients will be treated according to the standard clinical procedure

Exclusion criteria

Exclusion criteria: Patients will be treated according to the standard clinical procedure

Design outcomes

Primary

Measure	Time frame
Impact of Livopan on pain intensity during photodynamic therapy. Pain will be evaluated with the visual analog scale immediately after PDT	—

Secondary

Measure	Time frame
Number of therapy interruptions and time till first interruption (sec) during PDT. Data will be enteres in the CRF by the examiner.	—

Countries

Germany

Contacts

Public ContactChristine Fink

Universitätsklinik HeidelbergHautklinik

christine.fink@med.uni-heidelberg.de062215685133

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Mar 5, 2026