Platelet function assessed via Multiplate® and thrombomiR in patients with traumatic brain injury receiving aspirin: a prospective, observational pilot study.

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00006036

Enrollment

160

Registered

2014-04-02

Start date

2018-06-01

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

S06

Interventions

Group 1: target group: patients undergoing antiplatelet therapy with Aspirin and traumatic brain injury Intervention: assessment of platelet function via Multiplate and thrombomiR in addition to sta

single blood sampling (4,4ml) Intervention INDEPENDENT from the trial: cranial computed tomography (CCT) ad admission to the hospital and - in case of positive findings - repeated during hospital sta

Eligibility

Sex/Gender

All

Age

18 Years to 100 Years

Inclusion criteria

Inclusion criteria: positive findings in medical history regarding intake of acetylsalicylic acid (T-Ass®) clinical evidence of traumatic brain injury (GCS 4 – 14)

Exclusion criteria

Exclusion criteria: platelet count < 100G/l life expectancy < 12h surgical evacuation, intake of any other platelet inhibitor than aspirin

Design outcomes

Primary

Measure	Time frame
correlation between incidence/progression of traumatic intracranial haemorrhage in patients undergoing dual antiplatelet therapy and findings in impaired platelet function detected using Multiplate® analyser and thrombomiR testing	—

Countries

Austria

Contacts

Public ContactMarion Wiegele

AKH Wien Abteilung für Anästhesie, Intensivmedizin und Schmerztherapie

marion.wiegele@meduniwien.ac.at+43-1-40400/6820

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026