Sustained Attention as Mediator in Mindfulness-Based Cognitive Therapy for Depression

Sustained Attention as Mediator in Mindfulness-Based Cognitive Therapy for Depression - 8YZ

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00006014

Enrollment

100

Registered

2014-12-19

Start date

2014-07-01

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

F33

Interventions

Group 1: MBCT (mindfulness-based cognitive therapy) comprises eight weekly two-and-a-half-hour group sessions (eight to twelve participants) and at least 45 min of daily homework (six days a week) ove

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: (a) age between 18 and 65 years, right-handedness, normal hearing ability; (b) history of recurrent major depression with three or more previous episodes (c) commitment to homework compliance and to not initiating any changes in medication (starting, suspending, changing dosage) unless a relapse made it necessary.

Exclusion criteria

Exclusion criteria: (a) current major depressive episode, or presence of dysthymic disorder; (b) presence of substance abuse, eating disorder, or obsessive-compulsive disorder; (c) presence or history of one or more of the following: bipolar disorder, borderline personality disorder, schizophrenia or schizoaffective disorder, epilepsy or other neurological disorder, organic mental disorder, pervasive developmental delay; (d) significant experience with any kind of practice including mindfulness and/or concentration as important element (e.g. meditation, meditative prayer, autogenic training, meditative yoga, etc.).

Design outcomes

Primary

Measure	Time frame
Patient's electroencephalogram (EEG) is measured during two meditation tasks at 3 time points: pre-therapy, post-therapy, and at follow-up, 1 year after the end of therapy. Event-related brain potentials (ERP) are obtained from the EEG, especially the contingent negative variation (CNV), a component elicited by a simple stimulus and reflecting the allocation of attentional resources during meditation. The quality of mindfulness and sustained attention during the two meditation tasks is assessed also by the Toronto Mindfulness Scale (TMS), a self-report measure administered immediately after each task at the same 3 time points as the CNV.	—

Measure

Time frame

Patient's electroencephalogram (EEG) is measured during two meditation tasks at 3 time points: pre-therapy, post-therapy, and at follow-up, 1 year after the end of therapy. Event-related brain potentials (ERP) are obtained from the EEG, especially the contingent negative variation (CNV), a component elicited by a simple stimulus and reflecting the allocation of attentional resources during meditation. The quality of mindfulness and sustained attention during the two meditation tasks is assessed also by the Toronto Mindfulness Scale (TMS), a self-report measure administered immediately after each task at the same 3 time points as the CNV.

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Secondary

Measure	Time frame
Presence and severity of depressive symptoms is monitored weekly by the Center for Epidemiologic Studies Depression Scale (CES-D) administered via internet, starting with the first week of therapy and ending 1 year after the end of therapy (i.e. 60 measuring points: 8 during therapy, 52 during follow-up). Relapse/recurrence of Major Depression during the 1-year follow-up period is assessed retrospectively by the Longitudinal Interval Follow-up Evaluation (LIFE).	—

Measure

Time frame

Presence and severity of depressive symptoms is monitored weekly by the Center for Epidemiologic Studies Depression Scale (CES-D) administered via internet, starting with the first week of therapy and ending 1 year after the end of therapy (i.e. 60 measuring points: 8 during therapy, 52 during follow-up). Relapse/recurrence of Major Depression during the 1-year follow-up period is assessed retrospectively by the Longitudinal Interval Follow-up Evaluation (LIFE).

—

Countries

Germany

Contacts

Public ContactLilian Ohlrogge

Eberhard Karls UniversitätFachbereich PsychologieKlinische Psychologie und Psychotherapie

lilian.ohlrogge@uni-tuebingen.de07071 2974379

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026