F31
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Bipolar I and Bipolar II, remitted (symptom free for at least 4 weeks), on stable medication, 18 to 55 years of age, at least one previous affective episode in the last two years, giving informed consent
Exclusion criteria
Exclusion criteria: Patients with more than six previous episodes, rapid cycling, acute suicidal, schizo-affective disorder, schizophrenia, ADHD, substance use disorder (last 6 month), borderline personality disorder, informed consent, withdrawing informed consent, not taking medication
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Rate of relapse (a new affective episode or re-hospitalization) assessed by Longitudial Follow-up Evaluaion interview at 6, 12, and 18 months after inclusion into study. | — |
Secondary
| Measure | Time frame |
|---|---|
| Symptom Rating (Mania self ratings, Quick Depression Inventory self rating, Young Mania Scale and Quick Inventory of Depressive Symptoms clinician ratings); missed days at work/school, spent days in Hospital, health costs, improved compliance to medical treatment, social functioning, life Quality, normalized neurobiological functioning (net work of amygdala, striatum, medial prefrontal cortex, temporo-frontal cortex, subcortical structurs). | — |
Countries
Germany
Contacts
Eberhard Karls UniversitätFachbereich PsychologieKlinische Psychologie und Psychotherapie