Influence of mitochondrial DNA on immune function in sepsis: a prospective observational trial

Influence of mitochondrial DNA on immune function in sepsis: a prospective observational trial - mitochondrial DNA in sepsis

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00006012

Enrollment

180

Registered

2014-07-11

Start date

2011-01-01

Completion date

Unknown

Last updated

2025-10-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

A41 R57.2

Interventions

Group 1: patients with severe sepsis on the first day of diagnosing sepsis. Patients characteristics were documented and blood was withdrawn for mtDNA analysis, cytokine measurements or genexpression

Eligibility

Sex/Gender

All

Age

18 Years to 90 Years

Inclusion criteria

Inclusion criteria: Sepsis as defined by Bone et al.

Exclusion criteria

Exclusion criteria: Age < 18 yr.; mental disorder; patients who refused study participation

Design outcomes

Primary

Measure	Time frame
serum concentration of mitochondrial DNA	—

Secondary

Measure	Time frame
30 day mortality	—

Countries

Germany

Contacts

Public ContactSimon Schäfer

Universitätsklinikum Essen

simon.schaefer@uni-due.de0049-201-723-84436

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026