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Influence of collagen hydrolysate on muscle mass in subjects with sarcopenia

Influence of collagen hydrolysate on muscle mass in subjects with sarcopenia

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
DRKS
Registry ID
DRKS00006003
Enrollment
60
Registered
2014-04-17
Start date
2013-02-17
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

R54

Interventions

Group 1: U1: Initial examination with control of inclusion criteriae. 3 Month intervention period with strength training (3 times 60 min/week) with daily ingestion of 15 g collagen hydrolysate. U-2:

Sponsors

Universitätsklinik Freiburg Bewegungsmedizin und Sport
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
65 Years to 90 Years

Inclusion criteria

Inclusion criteria: 2x 30 healthy subjects aged > 65 years with sarcopenia class I or II (1/2 SD below the normal values of a young reference pooulation in a handgrip test). Ability to perform 1.25 Watt/kg bodyweight on a clycle ergometer without symptoms. stable weight and nutritional behaviour. No regular sports activity in the past (less that 1 h/week) No contraindications regarding sports activities according to the criteriae of the ACSM No contraindications againts supplememts.

Exclusion criteria

Exclusion criteria: contraindications regarding sports activities according to the criteriae of the ACSM, 2009. Diagnosis of cancer within the last 5 years. Allergy/aversion against animal protein Inability to perform a strenght training Arterial hypertension (RRsyst > 200 mmHg und/oder RRdiast > 105 mmHg) under resting conditions; Insulin dependant Diabetes mellitus type II Liver oder kidnes disease with a non-permission to ingest higher concentraions of protein.

Design outcomes

Primary

MeasureTime frame
Increase in muscle mass (lean body mass) following the 3 month strength training period using DEXA-measurements (compared to the pre-training status)

Secondary

MeasureTime frame
Increase in muscular power (isokinetic measurements) and improvement in postural control (Posturomed) follwoing the 3 month strenght training

Countries

Germany

Contacts

Public ContactDaniel König

Universitätsklinik Freiburg Bewegungsmedizin und Sport

Daniel.Koenig@uniklinik-freiburg.de004976127074950

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026