High risk patients with indication for anticoagulation with NOACs like atrial fibrillation, deep vein thrombosis and/or lung embolism.
Conditions
Interventions
Group 1: Non-interventional prospective study: observation of high risk patient with indication for anticoagulation with NOACs like atrial fibrillation, deep vein thrombosis and/or lung embolism. No a
Sponsors
Universitätsklinikums Köln
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: High risk patients with indication for anticoagulation with NOACs like atrial fibrillation, deep vein thrombosis and/or lung embolism. a) Patients with suspected under-/overdose like renal/liver failure and/or non-compliance and/or intoxication; b) Patients with high risk of bleeding, especially patients who will get a cardiac catheterization with the necessary of antiplatelet drugs.
Exclusion criteria
Exclusion criteria: < 18 years; no high risk patients with treatment with NOACs
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| During the treatment with NOACs of high risk patients we want to proof (endpoints): clinical parameters (compliance [MARS-D], drug-interactions [AiD-Klinik], polypharmacy [MAI-Index], bleeding risk [HASBLED-Score]), TDM and activity of clotting. | — |
Secondary
| Measure | Time frame |
|---|---|
| No secondary endpoints | — |
Countries
Germany
Contacts
Public ContactGuido Michels
Klinik III für Innere Medizin Herzzentrum des Universitätsklinikums Köln
Outcome results
None listed