Photoacustics in combination with high-resoloution ultrasound for non-invasive diagnostic of patients with chronic wounds- prospective study for clinical evaluation of a hemoglobin spray of oxygenation of the Wound

Photoacustics in combination with high-resoloution ultrasound for non-invasive diagnostic of patients with chronic wounds- prospective study for clinical evaluation of a hemoglobin spray of oxygenation of the Wound - NA

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00005993

Enrollment

Registered

2014-07-17

Start date

2014-03-13

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

L97

Interventions

Group 1: A patient with a chronic wound gets one 2 sec puff from a hemoglobin spray named Granulox for one time. The content of oxygen hemoglobin is measured in the wound before and after the applicat

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: 18 years, chronic wound longer than 8 weeks, size of the wound >4cm², adequate treatment of the disease is carried out.

Exclusion criteria

Exclusion criteria: • acute wounds • other types of chronic wounds • dependency • pregnancy and lactation • allergy against the ingredients of the hemoglobin spray • infection of the wound • sklerosis of the wound ground • Severe systemic diseases (ASA<4) like renal failure and cancer

Design outcomes

Primary

Measure	Time frame
The content of oxygenated hemoglobin is measured before the application of the hemoglobin spray, 5 min and 20 min after with photoacustic tomography.	—

Countries

Germany

Contacts

Public ContactJulia Leyh

Hautklinik Essen

julia.leyh@web.de020173285365

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Mar 7, 2026