Patients in need of implant therapy with an expected peri-implant bone defect in the maxilla or mandible. K08.1
Conditions
Interventions
Group 1: xenogenic bone block substitute (test) (BioOss Spongiosa Block, Geistlich Pharma AG)
Group 2: particulated xenogenic mineral (control) (BioOss Spongiosa granules, Geistlich Pharma AG)
Sponsors
University of Zurich, Center of Dental Medicine, Clinic of Reconstructive Dentistry
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1) at least 18 years old 2) in need of at least one implant with an expected peri-implant bone dehiscence in the maxilla or mandible 3) primary stability of the implant must be achieved. 4) Following implant placement, a type defect of 3 mm or more must be present for inclusion.
Exclusion criteria
Exclusion criteria: - Pregnant - Heavy smokers (>10 cigarettes per day) - Pipe and cigar smokers
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| to test whether or not the two different bone substitutes perform differently with respect to post-operative volume of augmented buccal bone 6 months after GBR (guided bone regeneration) procedure measured by radiology and histology | — |
Secondary
| Measure | Time frame |
|---|---|
| • Ossification of the bone substitute 6 month after GBR procedure (histological analysis) • Volume and contour of buccal soft-tissue 6 months after GBR procedure. • Implant survival and success rates 1 year after implant placement | — |
Countries
Switzerland
Contacts
Public ContactGoran I. Benic
University of Zurich, Center of Dental Medicine, Clinic of Reconstructive Dentistry
Outcome results
None listed