Integrated understanding of causes and mechanisms in mental disorders: Transdiagnostic neurocognitive biomarkers

Integrated understanding of causes and mechanisms in mental disorders: Transdiagnostic neurocognitive biomarkers - IntegraMent_MRI

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00005801

Enrollment

220

Registered

2014-10-29

Start date

2014-05-08

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Schizophrenia, bipolar disorder and major depression F20 F31 F33

Interventions

Group 1: 1. Patients with schizophrenia: MR-Scan, Blood sample for genetyping, clinical evaluation, extended neuropsychological tests, questionaires to assess psychological variables as well as envi

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: - Ability to understand study protocol and give written informed consent

Exclusion criteria

Exclusion criteria: - MR exclusion criteria (metal implants, brain surgery, permanent makeup) - Current alcohol or drug abuse

Design outcomes

Primary

Measure	Time frame
Identification of multivariate neurocognitive markers, that allow the transdiagnostic classification of patient subgroups according to biological criteria.	—

Secondary

Measure	Time frame
Find evidence for genetic contributions to disorder-specific and transdiagnostic neurocognitve markers.	—

Countries

Germany

Contacts

Public ContactAndreas Meyer-Lindenberg

Zentrales Institut für seelische Gesundheit, Abteilung Psychiatrie und Psychotherapie

a.meyer-lindenberg at zi-mannheim.de+49 621 1703 2001

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026