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Comparison of end-tidal control (ETC) of the Aisys® anesthesia machine and standard minimal-flow anesthesia with respect to consumption of gas and precision of target values of oxygen and volatile anesthetic

Comparison of end-tidal control (ETC) of the Aisys® anesthesia machine and standard minimal-flow anesthesia with respect to consumption of gas and precision of target values of oxygen and volatile anesthetic

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
DRKS
Registry ID
DRKS00005800
Enrollment
60
Registered
2014-02-20
Start date
2014-02-04
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Oxygen and volatile anesthetic consumption

Interventions

Group 1: Resident: end-tidal control with Aisys® anesthesia machine Group 2: Resident: minimal flow without end-tidal control Group 3: Consultant: end-tidal control with Aisys® anesthesia machine Grou

Sponsors

Zentrum für Anästhesiologie, Rettungs- und Intensivmedizin
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 50 Years

Inclusion criteria

Inclusion criteria: ASA I or II; elective surgery in general anesthesia anesthesia with remifentanil, rocuronium, and sevoflurane; planned procedure time > 60 min

Exclusion criteria

Exclusion criteria: ASA III to V; pregnancy allergy to or contraindication for the usage of midazolam, propofol, remifentanil, rocuronium, and sevoflurane; planned procedure time < 60 min known malignant hyperthermia

Design outcomes

Primary

MeasureTime frame
The consumption of sevoflurane will be estimated by weighing the vapor before and after the procedure. The consumption of oxygen and air will be collected via the interface of the anesthesia machine. The time and duration until the predefined values for the concentration of oxygen and sevoflurane and any discrepancy will be collected via the interface as well.

Secondary

MeasureTime frame
The number of necessary adjustments and the number of requests for an adjustment while using an anesthesia machine without closed loop feedbacks will be recorded. Hemodynamic values as well as peripheral oxygen saturation will be recorded as part of the routine anesthesia documentation.

Countries

Germany

Contacts

Public ContactIvo Brandes

Zentrum für Anästhesiologie, Rettungs- und Intensivmedizin

ibrande@gwdg.de+49 551 396051

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026