L40.5 L40.0
Conditions
Interventions
Group 1: Fluorescence-optical imaging in early detection of active psoriatic arthritis in psoriasis patients using ultrasound, clinical examination, fluorescence-optical imaging and early diagnosis qu
Sponsors
Fraunhofer IMEProjektgruppe TMPc/o Universitätsklinikum Frankurt/Main
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: Psoriasis vulgaris (dermatologic proven), risk of a muculoscelettal manifestation defined as nail psoriasis and/or musculoscelettal pain and/or swollen joints within 6 months, no known Psoriatic Arthritis, no biological therapy
Exclusion criteria
Exclusion criteria: known hypersensitivity against immunofluorescence-contrast agent, esp. ICG, wounds at hands, allergy against iodine, manifest hyperthyreosis, autonomy of thyroid adenomas, focal and diffuse thyroid autonomy, presence of a significant co-morbidity or severe and/or uncontrolled disease, that would effect patients safety and collide with results of the study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| non-inferiority of fluorescence-optical imaging to physical examination and ultrasound in detection of Psoriatic Arthritis out of Psoriasis Patients | — |
Secondary
| Measure | Time frame |
|---|---|
| Comparison of fluorescence-optical imaging to early-diagnosis questionnaires, physical examination and ultrasound in early detection of Psoriatic Arthrtitis | — |
Countries
Germany
Contacts
Public ContactFrank Behrens
Fraunhofer IMEProjektgruppe TMPc/o Universitätsklinikum Frankurt/Main
Outcome results
None listed