Small preterm infants R45.7
Conditions
Interventions
Group 1: Music therapy for 15 Minutes on three consequtive days
Sponsors
Neonatologie der Kinderklinik am Perinatalznetrum der LMU-München, Grosshadern
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: (1) preterm infants born at 500 -1499g birthweight; (2) On full enteral nutrition; (3) not on any analgesic or sedating drug; (4) within 48 hours prior to music exposition: no signs of infection (increased CrP), no surfactant treatment, no arterial hypotension, no need for systemic or inhaled steroids, no IVH of any grade, no blood glucose < 40 mg/dl, no blood transfusion, not on any respiratory support (5) Written parental consent.
Exclusion criteria
Exclusion criteria: (1) Small for gestational age below 3. percentile; (2) severe malformations; chromosomal aberrations, vitium cordis, (except patent ductus arteriosus or atrial septal defect (3) family history or manifest adrenal malfunction (e.g. Adreno-genital.syndrome); (4) IVH>/=°I; (5) negative hearing screen in any ear.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Primary outcome of the study is the salivary cortisol level, measured from saliva collected prior to live harp music by mass spectrometry, 25 minutes and 4 hours after pentatonic live harp exposition. | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary outcomes are the number of bradycardia below 100/min; the frequency of desaturations below 85% (mean values 4 hrs prior and 4 hrs after music) and the measured value of the bernese pain score for newborns prior to music, immediately after music, 40 min and 4 hours after Music | — |
Countries
Germany
Contacts
Public ContactAndreas W. Flemmer
Neonatologie der Kinderklinik am Perinatalznetrum der LMU-München, Grosshadern
Outcome results
None listed