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Determination of respiratory mechanics, arterial oxygenation and functional lung ventilation under a prospective change of the end-expiratory pressure in healthy, intubated and mechanically ventilated patients in the prone position.

Determination of respiratory mechanics, arterial oxygenation and functional lung ventilation under a prospective change of the end-expiratory pressure in healthy, intubated and mechanically ventilated patients in the prone position.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
DRKS
Registry ID
DRKS00005692
Enrollment
48
Registered
2014-02-26
Start date
2014-03-03
Completion date
Unknown
Last updated
2025-10-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

intraoperative, controlled ventilation

Interventions

Group 1: Patients with perioperative, controlled ventilation in prone position will be ventilated at 6 cmH2O PEEP level. After 15 minutes of ventilation the following parameters will be measured: (1)

Sponsors

Klinik für Anästhesiologie und IntensivmedizinUniversitätsklinikum Freiburg
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: controlled ventialtion, prone position, arterial blood pressure monitoring

Exclusion criteria

Exclusion criteria: age50), heart pacemaker, heart defibrillator and other active implant, valvular heart disease, language barrier

Design outcomes

Primary

MeasureTime frame
Calculation of the respiratory system compliance using airway pressure and tidal volume (measured by volume flow) at each PEEP level—

Secondary

MeasureTime frame
arterial oxygen partial pressure, measured by arterial blood gas sample, one measurement at each PEEP level; functional regional lung ventilation, measured by means of the electrical impedance tomography, one measurement at each PEEP level (5 min.)—

Countries

Germany

Contacts

Public ContactJohannes Spaeth

Klinik für Anästhesiologie und Intensivmedizin

johannes.spaeth@uniklinik-freiburg.de0761-270-23060

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026