O14.9
Conditions
Interventions
Group 1: Dopplersonographic measurement of cerebral hemodynamics (dynamic cerebral autoregulation and visual coupling) of women with preeclampsia within one week post partum and after 6 months. If the
Sponsors
Neurozentrum, Abteilung für Neurologie
Eligibility
Sex/Gender
Female
Age
18 Years to 45 Years
Inclusion criteria
Inclusion criteria: 1. Women within the first week post partum a) with preeclampsia b) without preeclampsia in this or a preceding pregnancy. 2. age 18 to 45 years. 3. Written informed consent.
Exclusion criteria
Exclusion criteria: 1. High-grade stenosis of cerebral arteries. 2. History of stroke, TIA, brain operation, brain tumor. 3. No ultrasound window for transtemporal ultrasound. 4. Epilepsy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Parameters of cerebral hemodynamics will be obtained in a transtemporal dopplersonographic evaluation of A. cerebri media and A. cerebri posterior. Part A: Cerebral autoregulation (phase or gain) 6 months post partum. Part B: Neurovascular coupling (resting flow velocity, overshoot flow velocity, steady-state flow velocity) 6 months post partum. | — |
Secondary
| Measure | Time frame |
|---|---|
| Cardiovascular risk factors (arterial hypertension, diabetes mellitus, increased BMI). Clinical data will be inquired by means of a questionnaire. Parameters of cerebral hemodynamics will be obtained in a transtemporal dopplersonographic evaluation of A. cerebri media and A. cerebri posterior. Part A: Cerebral autoregulation (phase or gain) 2 years post partum. Part B: Neurovascular coupling (resting flow velocity, overshoot flow velocity, steady-state flow velocity) 2 years post partum. | — |
Countries
Germany
Contacts
Public ContactWibke Janzarik
Zentrum für Kinder- und Jugendmedizin, Abteilung für Neuropädiatrie und Muskelerkrankungen
Outcome results
None listed