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Cerebral hemodynamics in patients with a history of preeclampsia

Cerebral hemodynamics in patients with a history of preeclampsia

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
DRKS
Registry ID
DRKS00005665
Enrollment
50
Registered
2014-01-23
Start date
2014-02-07
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

O14.9

Interventions

Group 1: Transtermporal dopplersonographic examination of A. cerebri media and A. cerebri posterior to evaluate the cerebral hemodynamics (dynamic cerebral autoregulation and visual coupling) of women

Sponsors

Neurozentrum, Abteilung für Neurologie
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 55 Years

Inclusion criteria

Inclusion criteria: 1. Women after at least one birth with or without preeclampsia, respectively. 2. Time interval to the last birth > 1 year and < 15 years. 3. Age 18 to 55 years. 4. Written informed consent to the study.

Exclusion criteria

Exclusion criteria: 1. Pregnancy at the time of study inclusion. 2. History of brain operation or brain tumor. 3. No ultrasound window for transtemporal ultrasound. 4. Epilepsy.

Design outcomes

Primary

MeasureTime frame
Using a one-time dopplersonographic ultrasound examination, parameters of dynamic cerebral autoregulation (phase and gain) will be evaluated.

Secondary

MeasureTime frame
Using a questionnaire history of cerebrovascular risk factors (hypertension, diabetes, increased BMI) and possible ischemic cerebrovascular events will be inquired. During the one-time dopplersonographic examination parameters of visual coupling (resting flow velocity, overshoot flow velocity, steady-state flow velocity) will be evaluated.

Countries

Germany

Contacts

Public ContactWibke Janzarik

Zentrum für Kinder- und Jugendmedizin, Abteilung für Neuropädiatrie und Muskelerkrankungen

wibke.janzarik@uniklinik-freiburg.de0049 761 270 43000

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026