Velopharyngeal sphincter morphology and function in healthy adults and patients with cleft lip and palate

Velopharyngeal sphincter morphology and function in healthy adults and patients with cleft lip and palate - VELOS

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00005663

Enrollment

Registered

2014-02-07

Start date

2014-02-07

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Q37 Q35

Interventions

Group 1: 30 healthy male (n=15) and female (n=15) adults (18-50 yrs.) A dynamic and static 3D MRI is conducted. Also a speech assessment. Group 2: 15 adult females with cleft palate only (CPO) (18-5

Eligibility

Sex/Gender

All

Age

18 Years to 50 Years

Inclusion criteria

Inclusion criteria: Controls: Body mass index (BMI) under 27, normal resonance Arm/group 2 and 3 (Adult males with unilateral cleft lip and palate and adult females with cleft palate only): Body mass index (BMI) under 27

Exclusion criteria

Exclusion criteria: Controls: MRI-Exclusioncriteria, cleft lip and palate, swallowing disorder, sleep apnea, muscleskelletal disorders, obesity Arm/group 2 and 3 (Adult males with unilateral cleft lip and palate and adult females with cleft palate only): MRI-Exclusioncriteria

Design outcomes

Primary

Measure	Time frame
Lenght, diameter, circumfence and angle of origin of the levator veli palatini muscle (LVP) and palatoglossus muscle (PG) measured by dynamic and static 3D MRI.	—

Countries

Germany

Contacts

Public ContactSandra Neumann

Forschungszentrum Jülich GmbH,Institut für Neurowissenschaften und Medizin (INM-3)

s.neumann@fz-juelich.de02461-614190

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026