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Pulse wave velocity and intima-media thickness as an indication of cardiovascular degeneration in patients after chemotherapy in childhood and adolescence.

Pulse wave velocity and intima-media thickness as an indication of cardiovascular degeneration in patients after chemotherapy in childhood and adolescence.

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
DRKS
Registry ID
DRKS00005642
Enrollment
110
Registered
2018-01-08
Start date
2015-11-24
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

C40 C41 C47 C64 C65 C71 C74 C81 C83 C84 C85.9 C86 C91 C92 C93 C95

Interventions

Group 1: Patients included during the regular cardiac check will receive a history, physical examination, ECG, echocardiography, sonographic intima-media thickness measurement on the carotid and a lon

Sponsors

Universistätsklinikum Halle
Lead Sponsor

Eligibility

Sex/Gender
All
Age
No minimum to 31 Years

Inclusion criteria

Inclusion criteria: All patients in the pediatric cardiology department of the MLU who are cared for in one year between the ages of 1-31 years with a condition after cardiotoxic therapy in the context of an oncological disease in children and adolescents. The primary chemotherapy of these patients is more than a year and the last chemotherapy is more than two months ago.

Exclusion criteria

Exclusion criteria: Patients whose primary chemotherapy is less than one year and whose last chemotherapy is less than two months old or who do not meet the inclusion criteria.

Design outcomes

Primary

MeasureTime frame
Pulse wave speed: When lying down, after a rest period of five minutes, the standardized system of the Mobil-O-Graphen® PWA (I.E.M., Stolberg, Germany) takes place on the left upper arm. Intima-media thickness: Intima-media thickness at the common carotid artery (ACC) with a linear sound head (IPx-7 L12-5 50, 12-5 MHz, Philipps) and the preset thyroid (24-42Hz) according to the "leading-edge" method trained doctor or doctoral student.

Countries

Germany

Contacts

Public ContactChirstian Dubau

Universitätsklinikum Halle

kinderkardiologie@uk-halle.de03455572611

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026