J44.89
Conditions
Interventions
Group 1: After obtaining written informed consent from the patients, spirometry and blood gases will be measured. EMG electrodes will be positioned in a semi-rucumbent position after cleansing the ski
Sponsors
Uniklinik Freiburg, Department für Innere Medizin, Klinik für Pneumologie
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Patients with advanced stable hypercapnic COPD and éstablished noninvasive mechanical ventilation
Exclusion criteria
Exclusion criteria: - severe hypoxia ((PaO2 10 ng/ml and/or CRP > 10 mg/dl) - missing cooperation - use of sedative or analgetic agents within the last 6h - body mass index > 30 kg/m2
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Differences in parasternal respiratory muscle activation (expressed as % of acitvation during maximal voluntary breathing maneuvers) applying electromyography during different modes respiratory muscle training (ITL vs TRB). Data recording and evaluation will be during the last breaths of each respiratory training session. | — |
Secondary
| Measure | Time frame |
|---|---|
| - resting EMG of the respiratory muscles (M. sternocleidomastoideus, parasternal muscles, diaphragm) for the right / left body side - maximal innervation as assessed by EMG during maximal voluntary breathing maneuvers (PImax, Sniff, TLC-breathing) - effect of respiratory muscle training on dynamic hyperinflation, as assesse by spirometric measurement of the inspiratory capacity | — |
Countries
Germany
Contacts
Public ContactStephan Walterspacher
Uniklinik Freiburg, Department für Innere Medizin, Klinik für Pneumologie
Outcome results
None listed